Targeted therapy treatments – with a twist!

Twisted Ribbons

UNC-Chapel Hill researchers have developed a therapeutic approach that harnesses helical amyloid fibers designed to untwist and release drugs in response to body temperature, according to a study published in Nature Communications.

headshot of Ronit Freeman
Ronit Freeman, senior author of the study and an associate professor of applied physical sciences.

“Understanding the structural and assembly properties of the beta-amyloid 42 peptide is crucial for advancing our knowledge of Alzheimer’s and developing targeted therapies for this devastating neurodegenerative disorder,” said Ronit Freedman, senior author of the study, “Uncovering Supramolecular Chirality Codes for the Design of Tunable Biomaterials,” and an associate professor in the department of applied physical sciences (APS).

Read more about this groundbreaking research below through our UNC news site!

Drug delivery platform manipulating amyloid proteins key to Alzheimer’s treatment – College of Arts and Sciences (unc.edu)